Fig 1: mRNA and protein expression analyses for genes involved in fatty acid metabolismData are mean ± SEM (n = 23–25 for CON; n = 22–25 for patients with type 2 diabetes mellitus), two-tailed Mann–Whitney U test. **p < 0.01, ***p < 0.001. Data were analyzed for relative expression differences using peptidylprolyl isomerase A (PPIA) as reference gene with standard Ct method. Glucose-tolerant humans (CON), patients with type 2 diabetes mellitus (T2D). a mRNA expression levels of free fatty acid receptor 2 (FFAR2), b protein expression levels of FFAR2, c mRNA expression levels of free fatty acid receptor 4 (FFAR4), d protein expression levels of FFAR4, e mRNA expression levels of stearoyl-CoA desaturase-1 (SCD1), f protein expression levels of SCD1